Physiological mechanisms of gastric acidity and consequences of acid hypersecretion

Physiological mechanisms of gastric acidity and consequences of acid hypersecretion

Gastric acid (HCl) is produced by parietal cells. Its main functions are as follows: to facilitate the digestion of proteins, activating pepsinogen into pepsin; assist the absorption of micronutrients such as iron, calcium and vitamin B12; and reduce the chance of enteric infections and bacterial overgrowth. However, when there is acid hypersecretion related to an …

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